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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (whole mount)
4 DPC

17 matching records from 17 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cdx2  caudal type homeobox 2   (Synonyms: Cdx-2)
Results  Reference
1J:332401 Abuhashem A, Chivu AG, Zhao Y, Rice EJ, Siepel A, Danko CG, Hadjantonakis AK, RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription. Genes Dev. 2022 Aug 18;36(13-14):770-89
1J:191079 Acampora D, Di Giovannantonio LG, Simeone A, Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition. Development. 2013 Jan 1;140(1):43-55
1J:238298 Acampora D, Omodei D, Petrosino G, Garofalo A, Savarese M, Nigro V, Di Giovannantonio LG, Mercadante V, Simeone A, Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast. Cell Rep. 2016 Jun 21;15(12):2651-64
1J:293567 Azami T, Bassalert C, Allegre N, Valverde Estrella L, Pouchin P, Ema M, Chazaud C, Regulation of the ERK signalling pathway in the developing mouse blastocyst. Development. 2019 Jul 25;146(14):dev177139
1*J:217512 Bessonnard S, De Mot L, Gonze D, Barriol M, Dennis C, Goldbeter A, Dupont G, Chazaud C, Gata6, Nanog and Erk signaling control cell fate in the inner cell mass through a tristable regulatory network. Development. 2014 Oct;141(19):3637-48
1J:115635 Elling U, Klasen C, Eisenberger T, Anlag K, Treier M, Murine inner cell mass-derived lineages depend on Sall4 function. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16319-24
1J:291217 Huyghe A, Furlan G, Ozmadenci D, Galonska C, Charlton J, Gaume X, Combemorel N, Riemenschneider C, Allegre N, Zhang J, Wajda P, Rama N, Vieugue P, Durand I, Brevet M, Gadot N, Imhof T, Merrill BJ, Koch M, Mehlen P, Chazaud C, Meissner A, Lavial F, Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling. Nat Cell Biol. 2020 Apr;22(4):389-400
1J:274673 Kamemizu C, Fujimori T, Distinct dormancy progression depending on embryonic regions during mouse embryonic diapause. Biol Reprod. 2019 May 1;100(5):1204-1214
1J:226048 Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L, Rao A, Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4236-45
1*J:203997 Krawchuk D, Honma-Yamanaka N, Anani S, Yamanaka Y, FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst. Dev Biol. 2013 Dec 1;384(1):65-71
1*J:316190 Lacko LA, Massimiani M, Sones JL, Hurtado R, Salvi S, Ferrazzani S, Davisson RL, Campagnolo L, Stuhlmann H, Novel expression of EGFL7 in placental trophoblast and endothelial cells and its implication in preeclampsia. Mech Dev. 2014 Aug;133:163-76
1J:104800 Niwa H, Toyooka Y, Shimosato D, Strumpf D, Takahashi K, Yagi R, Rossant J, Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell. 2005 Dec 2;123(5):917-29
1*J:138816 Plusa B, Piliszek A, Frankenberg S, Artus J, Hadjantonakis AK, Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. Development. 2008 Sep;135(18):3081-91
1J:331143 Sathyanarayanan A, Ing-Simmons E, Chen R, Jeong HW, Ozguldez HO, Fan R, Duethorn B, Kim KP, Kim YS, Stehling M, Brinkmann H, Scholer HR, Adams RH, Vaquerizas JM, Bedzhov I, Early developmental plasticity enables the induction of an intermediate extraembryonic cell state. Sci Adv. 2022 Nov 4;8(44):eabl9583
1*J:327814 Suzuki D, Sasaki K, Kumamoto S, Tanaka K, Ogawa H, Dynamic Changes of Gene Expression in Mouse Mural Trophectoderm Regulated by Cdx2 During Implantation. Front Cell Dev Biol. 2022;10:945241
1J:171449 Williams LH, Kalantry S, Starmer J, Magnuson T, Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development. 2011 May;138(10):2049-57
1J:327337 Zhao Y, Bai D, Wu Y, Zhang D, Liu M, Tian Y, Lu J, Wang H, Gao S, Lu Z, Maternal Ezh1/2 deficiency in oocyte delays H3K27me2/3 restoration and impairs epiblast development responsible for embryonic sub-lethality in mouse. Development. 2022 Aug 1;149(15):dev200316

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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory